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022028 Tozasertib CAS: 639089-54-6

Specifications
References
CAS Number
639089-54-6
Grade
Highly Purified
Molecular Formula
C₂₃H₂₈N₈OS
Molecular Weight
464.59
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
-20°C
N-[4-[[4-(4-Methyl-1-piperazinyl)-6-[(5-methyl-1H-pyrazol-3-yl)amino]-2-pyrimidinyl]thio]phenyl]cyclopropanecarboxamide; VX 680; MK 0457

A multikinase inhibitor once used for cancer treatment.

Synonyms
N-[4-[[4-(4-Methyl-1-piperazinyl)-6-[(5-methyl-1H-pyrazol-3-yl)amino]-2-pyrimidinyl]thio]phenyl]cyclopropanecarboxamide; VX 680; MK 0457
CAS Number
639089-54-6
Molecular Formula
C₂₃H₂₈N₈OS
Molecular Weight
464.59
Solubility
DMSO, Methanol
Melting Point
248-253°C (dec.)
Appearance
White Solid
Storage and Stability
Store at -20°C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
References
Ulisse, S., et al.: J. Endocrinol., 204, 135 (2010), McDermott, U., et al.: Cancer Res., 70, 1625 (2010), Donato, N., et al.: Biochem., Pharmacol., 79, 688 (2010),
USBio References
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