Neurexins are heavily glycosylated and processed neuronal transmembrane cell surface proteins likely involved in cell recognition and adhesion. Antibody Anti-Neurexin-1-alpha was made against a peptide immunogen corresponding to a stretch of aa’s in the extracellular domain of human Neurexin-1-alpha. Although the theoretical full length of Neurexin-1-alpha is 161kD, the protein detected in human brain lysates may show a band around 160kD and additional bands around 45kD as a possible result of the posttranslational processing previously reported.
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