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029694 RBBP9, Recombinant, Human, aa1-186, His-Tag (Putative Hydrolase RBBP9, Retinoblastoma-binding Protein 9, RBBP-9, Retinoblastoma-binding Protein 10, RBBP-10, B5T-overexpressed Gene Protein, Protein BOG, BOG, RBBP10) CAS:

Specifications
References
Grade
Highly Purified
Accession Number
NP_006597
Molecular Weight
23.1
EU Commodity Code
30021019
Shipping Temp
Blue Ice
Storage Temp
-20°C

Retinoblastoma binding protein, also known as RBBP9, localizes to both the nucleus and the cytoplasm. RBBP9 is a retinoblastoma binding protein that may play a role in the regulation of cell proliferation and differentiation. Specifically, RBBP9 interacts with retinoblastoma(Rb) and provides cellular resistance to the growth-inhibitory effects of TGFbeta1, thus facilitating the cellular transformation process.

Source
Recombinant corresponding to aa1-186 from human RBBP9, fused to His-tag at N-terminal expressed in E.coli.
Amino Acid Sequence
MGSSHHHHHH SSGLVPRGSH MASPSKAVIV PGNGGGDVTT HGWYGWVKKE LEKIPGFQCL AKNMPDPITA RESIWLPFME TELHCDEKTI IIGHSSGAIA AMRYAETHRV YAIVLVSAYT SDLGDENERA SGYFTRPWQW EKIKANCPYI VQFGSTDDPF LPWKEQQEVA DRLETKLHKF TDCGHFQNTE FHELITVVKS LLKVPA
Molecular Weight
~23.1kD (MALDI-TOF)
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Source
Recombinant, E. coli
Purity
≥95% (SDS-PAGE)
Concentration
~0.5mg/ml
Form
Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, 1mM DTT, 10% glycerol, 0.1M sodium chloride.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
References
1. Woitach J T., et al. (1998) Nat Genet. 19:371-374. 2. Woitach J T., et al. (1999) Cytogenet Cell Genet. 85:252-253.
USBio References
No references available
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