PRDM1

Clone Type

Monoclonal

Host

Mouse

Source

Human

Swiss Prot

O75626

Isotype

IgG1

Clone Number

5E7

Grade

Ascites

Applications

E WB

Crossreactivity

Hu Mo

Gene ID

639

Shipping Temp

Blue Ice

Storage Temp

-20°C

BLIMP1; PRDI-BF1; MGC118922; MGC118923; MGC118924; MGC118925; PRDM1

PRDM1/Blimp1 is a repressor of beta-interferon gene expression. This action is exerted by binding to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. The transcription of this gene is increased upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported.

Applications

Western Bloting: 1:500-1:2000. ELISA: Suggested dilution 1:10000. Optimal dilutions to be determined by the researcher.

Storage and Stability

May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunogen

Purified recombinant fragment of human PRDM1 expressed in E. coli.

Form

Supplied as a liquid, 0.03% sodium azide.

Purity

Ascites

Specificity

Human, Mouse