TLE1, ID

Clone Type

Monoclonal

Host

Mouse

Source

Human

Swiss Prot

Q04724

Isotype

IgG1

Clone Number

381CT18.5.1

Grade

Affinity Purified

Applications

E WB

Crossreactivity

Accession #

NP_005068.2

Gene ID

7088

Gene #

TLE1

Shipping Temp

Blue Ice

Storage Temp

-20°C

TLE1, Transducin-like enhancer protein 1, E(Sp1) homolog, Enhancer of split groucho-like protein 1

Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.

Applications

Suitable for use in Western Blot, ELISA.

Recommended Dilution

ELISA: 1:1,000 Western Blot: 1:100~250

Storage and Stability

May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Immunogen

TLE1 Mab is generated from mice immunized with a KLH conjugated synthetic peptide selected from the Central region of human TLE1.

Form

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Purity

Purified by Protein G affinity chromatography.

Specificity

Human

References

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010)|Carvalho, L.R., et al. Mol. Endocrinol. 24(4):754-765(2010)|Ali, S.A., et al. Proc. Natl. Acad. Sci. U.S.A. 107(9):4165-4169(2010)|Jagdis, A., et al. Am. J. Surg. Pathol. 33(12):1743-1751(2009)|Buscarlet, M., et al. PLoS ONE 4 (12), E8107 (2009)

USBio References

No references available

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031293 Mouse Anti-TLE1, ID (TLE1, Transducin-like enhancer protein 1, E(Sp1) homolog, Enhancer of split groucho-like protein 1)

Clone Type

Host

Source

Swiss Prot

Isotype

Clone Number

Grade

Applications

Crossreactivity

Accession #

Gene ID

Gene #

Shipping Temp

Storage Temp

TLE1, Transducin-like enhancer protein 1, E(Sp1) homolog, Enhancer of split groucho-like protein 1

References

USBio References

Conjugates

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