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034166-PE Rabbit Anti-CPM, ID (CPM, Carboxypeptidase M) (PE)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
P14384
Conjugate
PE
Isotype
IgG
Grade
Affinity Purified
Applications
FLISA IHC WB
Crossreactivity
Hu
Accession #
NP_938079.1; NP_001865.1; NP_001005502.1
Gene ID
1368
Gene #
CPM
Shipping Temp
Blue Ice
Storage Temp
4°C Do Not Freeze
Notes
Preservative Free
CPM, Carboxypeptidase M

The protein encoded by this gene is a membrane-bound arginine/lysine carboxypeptidase. Its expression is associated with monocyte to macrophage differentiation. This encoded protein contains hydrophobic regions at the amino and carboxy termini and has 6 potential asparagine-linked glycosylation sites. The active site residues of carboxypeptidases A and B are conserved in this protein. Three alternatively spliced transcript variants encoding the same protein have been described for this gene.

Applications
Suitable for use in Immunohistochemistry, Western Blot and FLISA. Other applications have not been tested.
Recommended Dilution
Immunohistochemistry: Formalin-fixed, paraffin-embedded sections Optimal dilutions to be determined by the researcher.
Storage and Stability
Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 212-241 in the central region of human CPM.
Form
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
Purity
Purified by Protein A and peptide affinity chromatography.
Specificity
Recognizes human CPM.
References
1. Rietschel, M., et al. Biol. Psychiatry 68(6):578-585 (2010) 2. Erickson-Johnson, M.R., et al. Mod. Pathol. 22(12):1541-1547 (2009) 3. Marquez-Curtis, L., et al. Stem Cells 26(5):1211-1220 (2008) 4. Zhang, X., et al. J. Biol. Chem. 283(12):7994-8004 (2008) 5. Elortza, F., et al. J. Proteome Res. 5(4):935-943 (2006)
USBio References
No references available
Conjugates
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