CTNND2, CT

Clone Type

Polyclonal

Host

Rabbit

Source

Human

Swiss Prot

Q9UQB3

Isotype

IgG

Grade

Affinity Purified

Applications

E IHC WB

Crossreactivity

Hu Mo

Accession #

NP_001323.1

Gene ID

1501

Gene #

CTNND2

Shipping Temp

Blue Ice

Storage Temp

-20°C

CTNND2, NPRAP, Catenin delta-2, Delta-catenin, GT24, Neural plakophilin-related ARM-repeat protein, Neurojungin

This gene encodes an adhesive junction associated protein of the armadillo/beta-catenin superfamily and is implicated in brain and eye development and cancer formation. The protein encoded by this gene promotes the disruption of E-cadherin based adherens junction to favor cell spreading upon stimulation by hepatocyte growth factor. This gene is overexpressed in prostate adenocarcinomas and is associated with decreased expression of tumor suppressor E-cadherin in this tissue. This gene resides in a region of the short arm of chromosome 5 that is deleted in Cri du Chat syndrome.

Applications

Suitable for use in Western Blot, Immunohistochemistry and ELISA. Other applications not tested.

Recommended Dilutions

Western Blot: 1:1000 Immunohistochemistry (FFPE): 1:10-1:50 Optimal dilutions to be determined by the researcher.

Storage and Stability

May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunogen

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 1131-1159 in the C-terminal region of human CTNND2, UniProt Accession #Q9UQB3.

Form

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide

Purity

Purified by Protein A affinity chromatography

Specificity

Recognizes human CTNND2. Species Crossreactivity: mouse

References

1. Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010). 2. Zhang, J., et al. Exp. Cell Res. 316(6):1070-1081 (2010). 3. Yang, I., et al. Mol. Cells 29(3):233-237 (2010). 4. Stenzel, N., et al. J. Cell. Sci. 122 (PT 18), 3374-3384 (2009). 5. Martins-de-Souza, D., et al. Eur Arch Psychiatry Clin Neurosci 259(3):151-163 (2009)

USBio References

No references available

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034339 Rabbit Anti-CTNND2, CT (CTNND2, NPRAP, Catenin delta-2, Delta-catenin, GT24, Neural plakophilin-related ARM-repeat protein, Neurojungin)

Clone Type

Host

Source

Swiss Prot

Isotype

Grade

Applications

Crossreactivity

Accession #

Gene ID

Gene #

Shipping Temp

Storage Temp

CTNND2, NPRAP, Catenin delta-2, Delta-catenin, GT24, Neural plakophilin-related ARM-repeat protein, Neurojungin

References

USBio References

Conjugates

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