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035250 Rabbit Anti-ETS2, ID (ETS2, Protein C-ets-2)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
P15036
Isotype
IgG
Grade
Affinity Purified
Applications
E FC IHC WB
Crossreactivity
Hu
Accession #
P15036; P15037; A1A4L6
Gene ID
2114
Gene #
ETS2
Shipping Temp
Blue Ice
Storage Temp
-20°C
ETS2, Protein C-ets-2

ETS transcriptions factors, such as ETS2, regulate numerous genes and are involved in stem cell development, cell senescence and death, and tumorigenesis. The conserved ETS domain within these proteins is a winged helix-turn-helix DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T of target genes.

Applications
Suitable for use in ELISA, Western Blot, Immunohistochemistry and Indirect Flow Cytometry. Other applications not tested.
Recommended Dilution
Western Blot: 1:1000 Immunohistochemistry (FFPE): 1:50-1:100 Indirect Flow Cytometry: 1:10-1:50 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 146-173 in the central region of human ETS2, UniProt Accession #P15036; P15037; A1A4L6.|Species sequence homology: bovine, mouse
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A and peptide affinity chromatography.
Specificity
Recognizes human ETS2.
References
1. Zabuawala, T., et al. Cancer Res. 70(4):1323-1333(2010) 2. Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009) 3. Shalaby, A.A., et al. Mod. Pathol. 22(8):996-1005(2009) 4. Sutter, W., et al. J Craniomaxillofac Surg 37(5):263-271(2009) 5. Staun-Ram, E., et al. Reprod. Biol. Endocrinol. 7, 135 (2009)
USBio References
No references available
Conjugates
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