HJURP, CT

Clone Type

Polyclonal

Host

Rabbit

Source

Human

Swiss Prot

Q8NCD3

Isotype

IgG

Grade

Affinity Purified

Applications

E FC IHC WB

Crossreactivity

Accession #

NP_060880.3

Gene ID

55355

Gene #

HJURP

Shipping Temp

Blue Ice

Storage Temp

-20°C

HJURP, FAKTS, FLEG1, URLC9, Holliday junction recognition protein, 14-3-3-associated AKT substrate, Fetal liver-expressing gene 1 protein, Up-regulated in lung cancer 9

HJURP is a centromeric protein that plays a central role in the incorporation and maintenance of histone H3-like variant CENPA at centromeres. Acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres. Directly binds Holliday junctions.

Applications

Suitable for use in Western Blot, Immunohistochemistry, Indirect Flow Cytometry, ELISA

Recommended Dilution

ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:10-50 Indirect Flow Cytometry: 1:10-50

Storage and Stability

May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunogen

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 559-588 in the C-terminal region of human HJURP.

Form

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Purity

Purified by Protein A and peptide affinity chromatography.

Specificity

Recognizes human HJURP.

References

1. Sebastiani, P., et al. Science (2010). 2. Shuaib, M., et al. Proc. Natl. Acad. Sci. U.S.A. 107(4):1349-1354(2010). 3. Hu, Z., et al. Breast Cancer Res. 12 (2), R18 (2010). 4. Dunleavy, E.M., et al. Cell 137(3):485-497(2009). 5. Foltz, D.R., et al. Cell 137(3):472-484(2009)

USBio References

No references available

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036613 Rabbit Anti-HJURP, CT (HJURP, FAKTS, FLEG1, URLC9, Holliday junction recognition protein, 14-3-3-associated AKT substrate, Fetal liver-expressing gene 1 protein, Up-regulated in lung cancer 9)

Clone Type

Host

Source

Swiss Prot

Isotype

Grade

Applications

Crossreactivity

Accession #

Gene ID

Gene #

Shipping Temp

Storage Temp

HJURP, FAKTS, FLEG1, URLC9, Holliday junction recognition protein, 14-3-3-associated AKT substrate, Fetal liver-expressing gene 1 protein, Up-regulated in lung cancer 9

References

USBio References

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