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036650-APC Rabbit Anti-HMMR, CT (HMMR, IHABP, RHAMM, Hyaluronan mediated motility receptor, Intracellular hyaluronic acid-binding protein, Receptor for hyaluronan-mediated motility, CD168) (APC)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
O75330
Conjugate
APC
Isotype
IgG
Grade
Affinity Purified
Applications
FLISA IHC WB
Crossreactivity
Hu
Accession #
NP_036616.2
Gene ID
3161
Gene #
HMMR
Shipping Temp
Blue Ice
Storage Temp
4°C Do Not Freeze
HMMR, IHABP, RHAMM, Hyaluronan mediated motility receptor, Intracellular hyaluronic acid-binding protein, Receptor for hyaluronan-mediated motility, CD168

The protein encoded by this gene is involved in cell motility. It is expressed in breast tissue and together with other proteins, it forms a complex with BRCA1 and BRCA2, thus is potentially associated with higher risk of breast cancer. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Applications
Suitable for use in FLISA, Western Blot and Immunohistochemisty. Other potential application, though not tested is Direct Flow Cytometry. Other applications not tested.
Recommended Dilutions
Immunohistochemistry: Formalin-fixed, paraffin-embedded sections Optimal dilutions to be determined by the researcher.
Storage and Stability
Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 668-697 in the C-terminal region of human HMMR.
Form
Supplied as a liquid in PBS, pH 7.2. Labeled with Allophycocyanin (APC).
Purity
Purified by Protein A and peptide affinity chromatography.
Specificity
Recognizes human HMMR.
References
1. Huang, T.W., et al. Biomaterials 31(26):6701-6709 (2010). 2. Nagel, S., et al. Exp. Hematol. 38(1):38-45 (2010). 3. Gust, K.M., et al. Neoplasia 11(9):956-963 (2009). 4. Shigeishi, H., et al. Int. J. Oncol. 34(6):1565-1571(2009). 5. Luczynski, W., et al. Neoplasma 56(5):428-434 (2009)
USBio References
No references available
Conjugates
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