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036992 Rabbit Anti-IL1RL2, ID (IL1RL2, IL1RRP2, Interleukin-1 receptor-like 2, Interleukin-1 receptor-related protein 2)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
Q9HB29
Isotype
IgG
Grade
Affinity Purified
Applications
E FC WB
Crossreactivity
Hu
Accession #
NP_003845.2
Gene ID
8808
Gene #
IL1RL2
Shipping Temp
Blue Ice
Storage Temp
-20°C
IL1RL2, IL1RRP2, Interleukin-1 receptor-like 2, Interleukin-1 receptor-related protein 2

The protein encoded by this gene is a member of the interleukin 1 receptor family. An experiment with transient gene expression demonstrated that this receptor was incapable of binding to interleukin 1 alpha and interleukin 1 beta with high affinity. This gene and four other interleukin 1 receptor family genes, including interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2), interleukin 1 receptor-like 1 (IL1RL1), and interleukin 18 receptor 1 (IL18R1), form a cytokine receptor gene cluster in a region mapped to chromosome 2q12.

Applications
Suitable for use in ELISA, Western Blot and Indirect Flow Cytometry. Other applications have not been tested.
Recommended Dilutions
Western Blot: 1:8000 Flow Cytometry (Indirect): 1:25 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 257-286 in the central region of human IL1RL2. Cellular Localization: Membrane; single-pass type 1 membrane protein.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A and peptide affinity chromatography.
Specificity
Recognizes human IL1RL2.
References
1. Davila, S., et al. Genes Immun. 11(3):232-238(2010). 2. Dubois, P.C., et al. Nat. Genet. 42(4):295-302(2010). 3. Nakki, A., et al. BMC Med. Genet. 11 (1), 50 (2010). 4. Hosgood, H.D. III, et al. Occup Environ Med 66(12):848-853(2009). 5. Solovieva, S., et al. J. Rheumatol. 36(9):1977-1986(2009)
USBio References
No references available
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