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037334 Rabbit Anti-KCNK10, CT (KCNK10, TREK2, Potassium channel subfamily K member 10, Outward rectifying potassium channel protein TREK-2, TREK-2 K(+) channel subunit)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
P57789
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_066984.1; NP_612190.1
Gene ID
54207
Gene #
KCNK10
Shipping Temp
Blue Ice
Storage Temp
-20°C
KCNK10, TREK2, Potassium channel subfamily K member 10, Outward rectifying potassium channel protein TREK-2, TREK-2 K(+) channel subunit

The protein encoded by this gene belongs to the family of potassium channel proteins containing two pore-forming P domains. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations, and is stimulated strongly by arachidonic acid and to a lesser degree by membrane stretching, intracellular acidification, and general anaesthetics. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq].

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KCNK10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 503-532 amino acids from the C-terminal region of human KCNK10.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human
References
Gierten, J., et al. Br. J. Pharmacol. 154(8):1680-1690(2008)|Huang, D., et al. Med. Hypotheses 70(3):618-624(2008)|Goldstein, S.A., et al. Pharmacol. Rev. 57(4):527-540(2005)|Gu, W., et al. J. Physiol. (Lond.) 539 (PT 3), 657-668 (2002) :|Goldstein, S.A., et al. Nat. Rev. Neurosci. 2(3):175-184(2001)
USBio References
No references available
Conjugates
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