LARP7, CT

Clone Type

Polyclonal

Host

Rabbit

Source

Human

Swiss Prot

Q4G0J3

Isotype

IgG

Grade

Affinity Purified

Applications

E WB

Crossreactivity

Accession #

NP_056269.1; NP_057732.2

Gene ID

51574

Gene #

LARP7

Shipping Temp

Blue Ice

Storage Temp

-20°C

LARP7, La-related protein 7, La ribonucleoprotein domain family member 7, P-TEFb-interaction protein for 7SK stability

LARP7 is a negative transcriptional regulator of polymerase II genes, acting by means of the 7SK RNP system. Within the 7SK RNP complex, the positive transcription elongation factor b (P-TEFb) is sequestered in an inactive form, preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation.

Applications

Suitable for use in Western Blot, ELISA

Recommended Dilution

ELISA: 1:1,000 Western Blot: 1:100-500

Storage and Stability

May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunogen

LARP7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 526-556 amino acids from the C-terminal region of human LARP7.

Form

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Purity

Purified by Protein A affinity chromatography.

Specificity

Human

References

Tyagi, M., et al. J. Virol. 84(13):6425-6437(2010)|Kalsi, G., et al. Hum. Mol. Genet. 19(12):2497-2506(2010)|Markert, A., et al. EMBO Rep. 9(6):569-575(2008)|Krueger, B.J., et al. Nucleic Acids Res. 36(7):2219-2229(2008)|He, N., et al. Mol. Cell 29(5):588-599(2008)

USBio References

No references available

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037682 Rabbit Anti-LARP7, CT (LARP7, La-related protein 7, La ribonucleoprotein domain family member 7, P-TEFb-interaction protein for 7SK stability)

Clone Type

Host

Source

Swiss Prot

Isotype

Grade

Applications

Crossreactivity

Accession #

Gene ID

Gene #

Shipping Temp

Storage Temp

LARP7, La-related protein 7, La ribonucleoprotein domain family member 7, P-TEFb-interaction protein for 7SK stability

References

USBio References

Conjugates

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