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039113 Rabbit Anti-NR1D2, ID (NR1D2, Nuclear receptor subfamily 1 group D member 2, Orphan nuclear hormone receptor BD73, Rev-erb-beta, V-erbA-related protein 1-related)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
Q14995
Isotype
IgG
Grade
Affinity Purified
Applications
E IHC WB
Crossreactivity
Hu
Accession #
NP_005117.3
Gene ID
9975
Gene #
NR1D2
Shipping Temp
Blue Ice
Storage Temp
-20°C
NR1D2, Nuclear receptor subfamily 1 group D member 2, Orphan nuclear hormone receptor BD73, Rev-erb-beta, V-erbA-related protein 1-related

This gene encodes a member of the nuclear hormone receptor family, specifically the NR1 subfamily of receptors. The encoded protein functions as a transcriptional repressor and may play a role in circadian rhythms and carbohydrate and lipid metabolism. Alternatively spliced transcript variants have been described.

Applications
Suitable for use in Western Blot, Immunohistochemistry, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:10-50
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
NR1D2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 265-294 amino acids from the Central region of human NR1D2.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human
References
Campos-de-Sousa, S., et al. J. Biol. Rhythms 25(2):132-137(2010)|Burris, T.P. Mol. Endocrinol. 22(7):1509-1520(2008)|Liu, A.C., et al. PLoS Genet. 4 (2), E1000023 (2008) :|Wang, J., et al. Biochim. Biophys. Acta 1783(2):224-236(2008)|Raghuram, S., et al. Nat. Struct. Mol. Biol. 14(12):1207-1213(2007)
USBio References
No references available
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