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039722 Rabbit Anti-PCDH1, NT (PCDH1, Protocadherin-1, Cadherin-like protein 1, Protocadherin-42)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
Q08174
Isotype
IgG
Grade
Affinity Purified
Applications
E IF IHC WB
Crossreactivity
Hu
Accession #
NP_115796.2
Gene ID
5097
Gene #
PCDH1
Shipping Temp
Blue Ice
Storage Temp
-20°C
PCDH1, Protocadherin-1, Cadherin-like protein 1, Protocadherin-42

This gene belongs to the protocadherin subfamily within the cadherin superfamily. The encoded protein is a membrane protein found at cell-cell boundaries. It is involved in neural cell adhesion, suggesting a possible role in neuronal development. The protein includes an extracelllular region, containing 7 cadherin-like domains, a transmembrane region and a C-terminal cytoplasmic region. Cells expressing the protein showed cell aggregation activity. Alternative splicing occurs in this gene.

Applications
Suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:10-50 Immunofluorescence: 1:10-50
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
PCDH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 186-214 amino acids from the N-terminal region of human PCDH1.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human
References
Koppelman, G.H., et al. Am. J. Respir. Crit. Care Med. 180(10):929-935(2009)|Rush, J., et al. Nat. Biotechnol. 23(1):94-101(2005)|Ballif, B.A., et al. Mol. Cell Proteomics 3(11):1093-1101(2004)|Ballif, B.A., et al. Mol. Cell Proteomics 3(11):1093-1101(2004)|Colland, F., et al. Genome Res. 14(7):1324-1332(2004)
USBio References
No references available
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