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039811 Rabbit Anti-PDE7B, CT (PDE7B, cAMP-specific 3',5'-cyclic phosphodiesterase 7B)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
Q9NP56
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_061818.1
Gene ID
27115
Gene #
PDE7B
Shipping Temp
Blue Ice
Storage Temp
-20°C
PDE7B, cAMP-specific 3',5'-cyclic phosphodiesterase 7B

The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a cAMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
PDE7B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 424-454 amino acids from the C-terminal region of human PDE7B.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)|Kestenbaum, B., et al. J. Am. Soc. Nephrol. 21(7):1223-1232(2010)|Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5):800-812(2010)|Ikeda, M., et al. Biol. Psychiatry 67(3):263-269(2010)|Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
USBio References
No references available
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