PGLYRP1, CT

Clone Type

Polyclonal

Host

Rabbit

Source

Human

Isotype

IgG

Grade

Affinity Purified

Applications

E WB

Crossreactivity

Accession #

O75594; NP_005082.1

Gene ID

8993

Gene #

PGLYRP1

Shipping Temp

Blue Ice

Storage Temp

-20°C

PGLYRP1, PGLYRP, PGRP, TNFSF3L, Peptidoglycan recognition protein 1, Peptidoglycan recognition protein short

PGLYRP1 is a pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria, and has bacteriostatic activity towards Gram-negative bacteria. Plays a role in innate immunity.

Applications

Suitable for use in Western Blot, ELISA

Recommended Dilution

ELISA: 1:1,000 Western Blot: 1:100-500

Storage and Stability

May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunogen

PGLYRP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 146-174 amino acids from the C-terminal region of human PGLYRP1.

Form

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Purity

Purified by Protein A affinity chromatography.

Specificity

Human

References

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)|Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)|Dukhanina, E.A., et al. Proc. Natl. Acad. Sci. U.S.A. 106(33):13963-13967(2009)|Rohatgi, A., et al. Atherosclerosis 203(2):569-575(2009)|Dukhanina, E.A., et al. Bull. Exp. Biol. Med. 145(2):191-193(2008)

USBio References

No references available

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039921 Rabbit Anti-PGLYRP1, CT (PGLYRP1, PGLYRP, PGRP, TNFSF3L, Peptidoglycan recognition protein 1, Peptidoglycan recognition protein short)

Clone Type

Host

Source

Isotype

Grade

Applications

Crossreactivity

Accession #

Gene ID

Gene #

Shipping Temp

Storage Temp

PGLYRP1, PGLYRP, PGRP, TNFSF3L, Peptidoglycan recognition protein 1, Peptidoglycan recognition protein short

References

USBio References

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