PVRL3, CT

Clone Type

Polyclonal

Host

Rabbit

Source

Human

Swiss Prot

Q9NQS3

Conjugate

APC

Isotype

IgG

Grade

Affinity Purified

Applications

FLISA WB

Crossreactivity

Accession #

NP_056295.1

Gene ID

25945

Gene #

PVRL3

Shipping Temp

Blue Ice

Storage Temp

4°C Do Not Freeze

PVRL3, PRR3, Poliovirus receptor-related protein 3, CDw113, Nectin-3, CD113

Nectins (e.g., PVRL1; MIM 600644) are immunoglobulin-like adhesion molecules that interact with afadin (AF6; MIM 159559). Afadin is an actin filament-binding protein that connects nectins to the actin cytoskeleton. The nectin-afadin system organizes adherens junctions cooperatively with the cadherin (see MIM 192090)-catenin (see MIM 116805) system in epithelial cells.

Applications

Suitable for use in Western Blot and FLISA. Other applications have not been tested.

Recommended Dilutions

Optimal dilutions to be determined by the researcher.

Storage and Stability

Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Note: Applications are based on unconjugated antibody.

Immunogen

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 507-536 in the C-terminal region of human PVRL3.

Form

Supplied as a liquid in PBS, pH 7.2. Labeled with Allophycocyanin (APC).

Purity

Purified by Protein A affinity chromatography.

Specificity

Recognizes human PVRL3.

References

1. Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010. 2. Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010). 3. Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009). 4. Yu, X., et al. Nat. Immunol. 10(1):48-57(2009). 5. Fujito, T., et al. J. Cell Biol. 171(1):165-173(2005)

USBio References

No references available

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040697-APC Rabbit Anti-PVRL3, CT (PVRL3, PRR3, Poliovirus receptor-related protein 3, CDw113, Nectin-3, CD113) (APC)

Clone Type

Host

Source

Swiss Prot

Conjugate

Isotype

Grade

Applications

Crossreactivity

Accession #

Gene ID

Gene #

Shipping Temp

Storage Temp

PVRL3, PRR3, Poliovirus receptor-related protein 3, CDw113, Nectin-3, CD113

References

USBio References

Conjugates

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