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041167-FITC Rabbit Anti-ROR1, NT (ROR1, NTRKR1, Tyrosine-protein kinase transmembrane receptor ROR1, Neurotrophic tyrosine kinase, receptor-related 1) (FITC)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
Q01973
Conjugate
FITC
Isotype
IgG
Grade
Affinity Purified
Applications
FLISA WB
Crossreactivity
Hu Mo
Gene ID
4919
Gene #
ROR1
Shipping Temp
Blue Ice
Storage Temp
-20°C
Notes
Preservative Free
ROR1, NTRKR1, Tyrosine-protein kinase transmembrane receptor ROR1, Neurotrophic tyrosine kinase, receptor-related 1

ROR1 is a receptor protein tyrosine kinase whose cellular role has not been determined. It is a type I membrane protein and belongs to the ROR subfamily of cell surface receptors. Studies of a similar protein in mouse suggest that this protein may interact with another receptor protein tyrosine kinase and may be involved in skeletal and cardiac development.

Applications
Suitable for use in FLISA and Western Blot. Other potential application, though not tested is Direct Flow Cytometry. Other applications not tested.
Recommended Dilutions
Optimal dilutions to be determined by the researcher.
Storage and Stability
Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Note: Applications are based on unconjugated antibody.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 32-62 in the N-terminal region of human ROR1.
Form
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein isothiocyanate (FITC).
Purity
Purified by Protein A and peptide affinity chromatography.
Specificity
Recognizes human ROR1 at ~104kD. |Species Crossreactivity: mouse.
References
1. Nomi, M., et al., Mol. Cell. Biol. 21(24): 8329-8335 (2001). 2. Reddy, U.R., et al., Genomics 41(2): 283-285 (1997). 3. Reddy, U.R., et al., Oncogene 13(7): 1555-1559 (1996). 4. Masiakowski, P., et al., J. Biol. Chem. 267(36): 26,181-26,190 (1992).
USBio References
No references available
Conjugates
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