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042329 Rabbit Anti-SSR2, CT (SSR2, TRAPB, Translocon-associated protein subunit beta, Signal sequence receptor subunit beta)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
P43308
Isotype
IgG
Grade
Affinity Purified
Applications
E FC IHC WB
Crossreactivity
Hu
Accession #
NP_003136.1
Gene ID
6746
Gene #
SSR2
Shipping Temp
Blue Ice
Storage Temp
-20°C
SSR2, TRAPB, Translocon-associated protein subunit beta, Signal sequence receptor subunit beta

The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein (alpha-SSR or SSR1) and a 22-kD glycoprotein (beta-SSR or SSR2). The human beta-signal sequence receptor gene (SSR2) maps to chromosome bands 1q21-q23. [provided by RefSeq].

Applications
Suitable for use in Western Blot, Immunohistochemistry, Indirect Flow Cytometry and ELISA. Other applications have not been tested.
Recommended Dilution
Western Blot: 1:1000 Immunohistochemistry (FFPE): 1:10-1:50 Indirect Flow Cytometry: 1:10-1:50 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 154-183 in the C-terminal region of human SSR2, UniProt Accession #P43308. Species sequence homology: bovine
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A and peptide affinity chromatography.
Specificity
Recognizes human SSR2.
References
1. Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : 2. Sikorska, M., et al. J. Neurosci. Res. 86(8):1680-1693(2008) 3. Zhang, H., et al. Nat. Biotechnol. 21(6):660-666(2003) 4. Wang, L., et al. FEBS Lett. 457(3):316-322(1999) 5. Dodson, G., et al. Curr. Opin. Struct. Biol. 8(2):189-194(1998)
USBio References
No references available
Conjugates
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