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042846 Rabbit Anti-TIMM50, NT (TIMM50, TIM50, Mitochondrial import inner membrane translocase subunit TIM50)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
Q3ZCQ8
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_001001563.1
Gene ID
92609
Gene #
TIMM50
Shipping Temp
Blue Ice
Storage Temp
-20°C
TIMM50, TIM50, Mitochondrial import inner membrane translocase subunit TIM50

Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Has some phosphatase activity in vitro; however such activity may not be relevant in vivo. Isoform 2 may participate in the release of snRNPs and SMN from the Cajal body.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
TIMM50 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74-104 amino acids from the N-terminal region of human TIMM50.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human
References
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :|Xu, H., et al. BMC Cell Biol. 6 (1), 29 (2005) :|Guo, Y., et al. J. Biol. Chem. 279(23):24813-24825(2004)|Yuryev, A., et al. Genomics 81(2):112-125(2003)|Yamamoto, H., et al. Cell 111(4):519-528(2002)
USBio References
No references available
Conjugates
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