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042867 Rabbit Anti-TLE2, CT (TLE2, Transducin-like enhancer protein 2, Enhancer of split groucho-like protein 2)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Mouse
Swiss Prot
Q04725
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Mo
Accession #
NP_003251.2; NP_001138234.1; NP_001138233.1
Gene ID
7089
Gene #
TLE2
Shipping Temp
Blue Ice
Storage Temp
-20°C
TLE2, Transducin-like enhancer protein 2, Enhancer of split groucho-like protein 2

TLE2 is a transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES (By similarity).

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
TLE2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 636-665 amino acids from the C-terminal region of human TLE2.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Mouse
References
He, Z., et al. J. Virol. 84(4):2047-2062(2010)|Arce, L., et al. BMC Cancer 9, 159 (2009) :|Higa, L.A., et al. Nat. Cell Biol. 8(11):1277-1283(2006)|Javed, A., et al. J. Cell. Sci. 113 (PT 12), 2221-2231 (2000) :|Grbavec, D., et al. Biochem. J. 337 (PT 1), 13-17 (1999) :
USBio References
No references available
Conjugates
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