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043636 Rabbit Anti-UPP2, CT (UPP2, Uridine phosphorylase 2)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E IHC WB
Crossreactivity
Hu Mo
Accession #
NP_001128570.1; O95045; NP_775491.1
Gene ID
151531
Gene #
UPP2
Shipping Temp
Blue Ice
Storage Temp
-20°C
UPP2, Uridine phosphorylase 2

Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose-or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Shows substrate specificity and accept uridine, deoxyuridine, and thymidine as well as the two pyrimidine nucleoside analogs 5-fluorouridine and 5-fluoro-2(')-deoxyuridine as substrates.

Applications
Suitable for use in Western Blot, Immunohistochemistry, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:50-100
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
UPP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 217-244 amino acids from the C-terminal region of human UPP2.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human, mouse
References
Maestrini, E., et al. Mol. Psychiatry 15(9):954-968(2010)|Lamesch, P., et al. Genomics 89(3):307-315(2007)|Johansson, M. Biochem. Biophys. Res. Commun. 307(1):41-46(2003)|Russell, R.L., et al. J. Biol. Chem. 276(16):13302-13307(2001)
USBio References
No references available
Conjugates
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