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044523 ANGPTL3, Recombinant, Human (Angiopoietin-like Protein 3, Angiopoietin-5, ANG-5) CAS:

Specifications
References
Grade
Highly Purified
Swiss Prot
Q9Y5C1
Molecular Weight
60
EU Commodity Code
30021019
Shipping Temp
Blue Ice
Storage Temp
-70°C
Angiopoietin-like Protein 3, Angiopoietin-5, ANG-5

ANGPTL3 (Angiopoietin-like protein 3) regulates angiogenesis and also directly regulates lipid, glucose, and energy metabolism.

Human ANGPTL3 (aa1-460) is fused at the C-terminus to a FLAG®-tag expressed in HEK 293 cells (NM_014495.3)
Biological Activity
Activates ERK phosphorylation in THP-1 cells.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -70°C. Aliquots are stable for 6 months after receipt at -70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Source
Recombinant, HEK293 cells
Purity
≥90% (SDS-PAGE)
Form
Supplied as a lyophilized powder from PBS, pH 7.4, 100mM sodium chloride, 2.2mM potassium chloride.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
References
1. Y. Li, et al.; Acta Biochim. Biophys. Sin. (Shanghai) 40, 459 (2008). 2. H.E. Broxmeyer, et al.; Blood Cells Mol. Dis. 3. Ando, Y., et al., J. Lipid Res. 44: 1216-1223. 4. Lee, E-Chiang, et al., J. Biol. Chem. 284:13735-13745.
USBio References
No references available
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