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044557 ANGPTL7, Recombinant, Human (Angiopoietin-like Protein 7, Cornea-derived Transcript 6 Protein) CAS:

Specifications
References
Grade
Purified
Swiss Prot
O43827
Molecular Weight
45
EU Commodity Code
30021019
Shipping Temp
Blue Ice
Storage Temp
4°C/-20°C
Angiopoietin-like Protein 7, Cornea-derived Transcript 6 Protein

ANGPTL7 (Angiopoietin-like protein 7) is expressed in various tissues and regulates angiogenesis. Human ANGPTL7 was characterized as a potent target gene of the WNT/beta-catenin signaling pathway, and is a pharmacogenomics target in the fields of oncology and regenerative medicine.

Biological Activity
Activates ERK phosphorylation in THP-1 cells.
Sequence
Human ANGPTL7 (aa 1-346) is fused at the C-terminus to a FLAG®-tag.
Storage and Stability
Short-term Storage: +4°C Long-term Storage: -20°C Working aliquots are stable for up to 3 months when stored at -20°C.
Source
Recombinant, HEK293 cells
Purity
>90% (SDS-PAGE)
Concentration
~0.5mg/ml
Form
Supplied as a liquid from a 0.2um-filtered solution in PBS, pH 7.2.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
References
Product Reference: |●Angiopoietin-like-2 and -3 act through their coiled-coil domains to enhance survival and replating capacity of human cord blood hematopoietic progenitors: H.E. Broxmeyer, et al.; Blood Cells Mol. Dis. (Epub ahead of print) (2011)|●
USBio References
No references available
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