Delta-like Protein 1, Delta1
The Notch ligand delta-like protein 1 (DLL1) is essential for postnatal arteriogenesis and contributes to tumor progression. DLL1 is involved in differentiation and self-renewal of adipocyte stem cells. Blocks the differentiation of progenitor cells into the B cell lineage while promoting the emergence of a population of cells with the characteristics of a T cell/NK-cell precursor.
Recombinant protein corresponding to aa1-545 from the signal peptide and extracellular domain of human DLL1, fused at the C-terminus to a FLAG®-tag, expressed in HEK 293 cells.
Biological Activity
Inhibits adipogenesis of mesenchymal stem cells.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Source
Recombinant, HEK293 cells
Form
Supplied as a liquid from a 0.2um-filtered solution in PBS, pH 7.2. No preservative added.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.