Galactofuranose-binding Lectin, Intestinal Lactoferrin Receptor, Intelectin-1, Endothelial Lectin HL-1, Omentin 1
Omentin (Intelectin-1) is highly expressed in omental adipose tissue, small intestine and various other tissues. Omentin has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. It increases AKT phosphorylation in the absence and presence of insulin. It was suggested to play a role in the defense system against microorganisms by recognizing carbohydrate chains of pathogens and bacterial components containing galactofuranosyl residues.
Sequence
Human omentin (aa17-313) is fused at the N-terminus to a FLAG®-tag, expressed in CHO cells.
Biological Activity
Enhances glucose transport mediated by insulin.
Endotoxin
<0.1EU/ug (LAL test; Lonza).
Storage and Stability
Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Source
Recombinant, Human, CHO cells
Concentration
~0.1mg/ml (after reconstitution)
Form
Supplied as a lyophilized powder in PBS. Reconstitute with 100ul sterile ddH2O.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
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