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045137 Penicillide (Vermixocin A, Antibiotic AS 186A, Antibiotic MC 140) CAS: 55303-92-9

Specifications
References
CAS Number
55303-92-9
Grade
Highly Purified
Molecular Formula
C21H24O6
Molecular Weight
372.4
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
4°C/-20°C
Vermixocin A, Antibiotic AS 186A, Antibiotic MC 140

Plant growth inhibitor. Acyl-CoA-cholesterol acyltransferase (ACAT) inhibitor. Anticancer compound. Cytotoxic. Non-peptidic oxytocin receptor antagonist. Calpain inhibitor.

Source
Isolated from Penicillium sp.
Synonyms
Vermixocin A; Antibiotic AS 186A; Antibiotic MC 140
CAS Number
55303-92-9
Molecular Formula
C21H24O6
Molecular Weight
372.4
Solubility
DMSO, ethanol or methanol
Appearance
Supplied as an off-white solid.
Purity
≥95% (HPLC)
Storage and Stability
Store at -20°C. Keep cool and dry. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Purity
≥95% (HPLC)
Form
Supplied as an off-white solid.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
References
Product Reference: |●Structure of penicillide, a new metabolite produced by a Penicillium sp.: T. Sassa, et al.; Tetrahedron Lett. 15, 3941 (1974) |●Penicillide and dehydroisopenicillide from Talaromyces derxii: K. Suzuki, et al.; Phytochemistry 30, 2096 (1991)|●Purpactins, new inhibitors of acyl-CoA:cholesterol acyltransferase produced by Penicillium purpurogenum. III. Chemical modification of purpactin A: H. Nishida, et al.; J. Antibiot. (Tokyo) 44, 152 (1991)|●Vermixocins A and B, two novel metabolites from Penicillium vermiculatum: B. Proksa, et al.; J. Antibiot. (Tokyo) 45, 1268 (1992)|●Potent, non-peptidic oxytocin receptor antagonists from a natural source: G.M. Salituro, et al.; Bioorg. Med. Chem. Lett. 3, 337 (1993)|●AS-186 compounds, new inhibitors of acyl-CoA: cholesterol acyltransferase from Penicillium asperosporum KY1635: K. Kuroda, et al.; J. Antibiot. (Tokyo) 47, 16 (1994)|●Penicillide, a Nonpeptide Calpain Inhibitor, Produced by Penicillium sp. F60760: M.C: Chung, et al.; J. Microbiol. Biotechnol. 8, 188 (1998)
USBio References
No references available
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