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045146 Phomoxanthone A CAS: 359844-69-2

Specifications
References
CAS Number
359844-69-2
Grade
Highly Purified
Molecular Formula
C38H38O16
Molecular Weight
750.7
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
-20°C

Anticancer compound. Shows antimalarial and antitubercular activity. Cytotoxic against several cancer cell lines. Antibacterial against Gram-positive bacteria and antifungal.

CAS Number
359844-69-2
Source
Isolated from fungus Phoma sp.
Molecular Formula
C38H38O16
Molecular Weight
750.7
Purity
≥97% (HPLC)
Appearance
Off-white to yellow solid.
Solubility
DMSO. Slightly soluble in ethanol.
Note
P. Boehler (2018) describes that Phomoxanthone A becomes unstable if dissolved in DMSO, and readily isomerizes into the essentially non-toxic compound dicerandrol C. We advise therefore to dissolve the compound in DMSO immediately before usage.
Storage and Stability
Store at -20°C. Keep cool and dry, and protect from light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Purity
≥97% (HPLC)
Form
Off-white to yellow solid.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
References
1. Phomoxanthones A and B, novel xanthone dimers from the endophytic fungus Phomopsis species: M. Isaka, et al.; J. Nat. Prod. 64, 1015 (2001)|2. X-ray Structure Determination, Absolute Configuration and Biological Activity of Phomoxanthone A: B. Elsässer, et al.; Eur. J. Org. Chem. 2005, 4563 (2005)|3. Anticancer compounds derived from fungal endophytes: their importance and future challenges: R.N. Kharwar, et al.; Nat. Prod. Rep. (Epub ahead of print) (2011)
USBio References
No references available
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