Pifithrin-alpha CAS 60477-34-1

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045150 Pifithrin-alpha (cyclic) hydrobromide (2-(4-Methylphenyl)imidazo-5,6,7,8-tetrahydrobenzothiazole . HBr) CAS: 60477-34-1

Specifications

References

CAS Number

60477-34-1

Grade

Highly Purified

Molecular Formula

C16H16N2S . HBr

Molecular Weight

268.4809

EU Commodity Code

38220090

Shipping Temp

Blue Ice

Storage Temp

-20°C

2-(4-Methylphenyl)imidazo-5,6,7,8-tetrahydrobenzothiazole . HBr

Stable analog of pifithrin-alpha. p53 inhibitor.

Storage and Stability

Short-term Storage: +4°C Long-term Storage: -20°C Stable for at least 2 years after receipt when stored at -20°C.

Purity

>98% (NMR)

Important Note

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

References

Product Reference: |●Novel cyclized Pifithrin-alpha p53 inactivators: synthesis and biological studies: Bioorg. Med. Chem. Lett. 15, 1561 (2005)|●Imino-tetrahydro-benzothiazole derivatives as p53 inhibitors: discovery of a highly potent in vivo inhibitor and its action mechanism: N. Pietrancosta, et al.; J. Med. Chem. 49, 3645 (2006)|●