HSD17B8

Clone Type

Polyclonal

Host

Rabbit

Source

Human

Isotype

IgG

Grade

Serum

Applications

IP WB

Crossreactivity

Accession #

NM_014234.3, NP_055049.1

Shipping Temp

Blue Ice

Storage Temp

-20°C

NAD-dependent 17-beta-hydroxysteroid dehydrogenase with highest activity towards estradiol. Has very low activity towards testosterone. The heteroteramer with CBR4 has NADH-dependent 3-ketoacyl-acyl carrier protein reductase activity. May play a role in biosynthesis of fatty acids in mitochondria.

Applications

Suitable for use in Immunoprecipitation and Western Blot. Other applications not tested.

Recommended Dilution

Optimal dilutions to be determined by the researcher.

AA Sequence

MASQLQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITGTSVEVTGGLFM

Storage and Stability

May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunogen

Full length human HSD17B8, aa1-261 (NP_055049.1).

Form

Supplied as a liquid.

Purity

Serum

Specificity

Recognizes human HSD17B8.

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