IMP-3, Recombinant, Human CAS

Grade

Highly Purified

Swiss Prot

O00425

Applications

E WB

EU Commodity Code

30021019

Shipping Temp

Dry Ice

Storage Temp

-70°C

IMP-3, a member of the insulin-like growth factor-II (IGF-II) mRNA-binding protein (IMP) family, is expressed mainly during embryonic development and in some tumors. IMP-3 is considered to be an oncofetal protein.

Source

Recombinant protein corresponding to human IMP-3, expressed in E. coli.

Applications

Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilution

Optimal dilutions to be determined by the researcher.

Storage and Stability

Aliquot to avoid repeated freezing and thawing and store at -70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Source

E. coli

Purity

~90% (Nickel NTA Affinity Chromatography)

Concentration

As reported

Form

Supplied as a liquid in 20mM Tris-HCl, 150mM sodium chloride, 1mM EDTA, 5mM glutathione, 0.5mM GSSH, 10% glycerol.

Important Note

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

References

1. Liao (2005) The RNA-binding protein IMP-3 is a translational activator of insulin-like growth factor II leader-3 mRNA during proliferation of human K562 leukemia cells. J Biol Chem 280(18):18517-24.|2. Goodenough UW (1993) Activation of adenylyl cyclase in Chlamydomonas reinhardtii by adhesion and by heat. J Cel Biol 122(1):137-47.

USBio References

No references available

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149546 IMP-3, Recombinant, Human (Insulin-like Growth Factor 2 mRNA Binding Protein 3, IGF2 mRNA-binding Protein 3, IGF2BP3, IMP3, IGF-II mRNA-binding Protein 3, CT98, KH Domain-containing Protein Overexpressed in Cancer, hKOC, KOC1, VICKZ Family Member 3, VICKZ3) CAS:

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