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149547 Survivin, Recombinant, Human (Apoptosis Inhibitor 4, Apoptosis Inhibitor-4, API4, Apoptosis Inhibitor Survivin, Baculoviral IAP Repeat-containing 5, BIRC5, BIRC-5, EPR1, EPR-1, IAP4) CAS:

Specifications
References
Grade
Highly Purified
Swiss Prot
O15392
Applications
E WB
EU Commodity Code
30021019
Shipping Temp
Dry Ice
Storage Temp
-70°C

Survivin is a member of the inhibitor of apoptosis protein (IAP) family, that has been implicated in both control of cell division and inhibition of apoptosis.

Source
Recombinant protein corresponding to human Survivin, expressed in E. coli.
Applications
Suitable for use in ELISA and Western Blot. Other applications not tested.
Recommended Dilution
Optimal dilutions to be determined by the researcher.
Storage and Stability
Aliquot to avoid repeated freezing and thawing and store at -70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Source
E. coli
Purity
~90% (Nickel NTA Affinity Chromatography)
Concentration
As reported
Form
Supplied as a liquid in 20mM Tris-HCl, 150mM sodium chloride, 1mM EDTA, 5mM glutathione, 0.5mM GSSH, 10% glycerol.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
References
1. Daidone MG (2005) Survivin as a target for new anticancer interventions. J Cell Mol Med 9(2): 360-72.|2. Altierei DC (1997) A novel anti-apoptosis gene, surviving espressed in cancer and lymphoma. Nat Med 3:917-21.
USBio References
No references available
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