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158581 1,1,1-Trifluoromethanesulfonic Acid Tris(1-methylethyl)silyl Ester CAS: 80522-42-5

Specifications
References
CAS Number
80522-42-5
Grade
Highly Purified
Molecular Formula
C10H21F3O3SSi
Molecular Weight
306.42
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
RT/4°C
TIPSOTf; Triisopropyl(trifluoromethanesulfonato)silane; Triisopropylsilyl Triflate; Triisopropylsilyl Trifluoromethanesulfonate

1,1,1-Trifluoromethanesulfonic Acid Tris(1-methylethyl)silyl Ester is used in the synthesis of potent BRAF kinase inhibitors used in the therapeutic treatment of melanoma. Also used in the synthesis of antitumor antibiotic (+)-FR900482.

Solubility
Chloroform, Ethyl Acetate
References
Niculescu-Duvaz, D. et al.: Bioorg. Med. Chem., 21, 1284 (2013); Fellows, I. et al.: J. Am. Chem. Soc., 122, 10781 (2000);
USBio References
No references available
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