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160779 3,4-Epoxy-6-keto-4a,5-ene Simvastatin CAS: 1795790-98-5

Specifications
References
CAS Number
1795790-98-5
Grade
Highly Purified
Molecular Formula
C25H36O7
Molecular Weight
448.55
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
-20°C
2,2-Dimethylbutanoic Acid� (1S,7R,8R,8aR)-1,2,3,4,6,7,8,8a-Octahydro-3,7-dimethyl-3,4-epoxy-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl Ester

3,4-Epoxy-6-keto-4A,6-ene Simvastatin is an impurity of Simvastatin (S485000), a synthetic derivative of a fermentation product of Aspergillus terreus and a competitive inhibitor of HMG-CoA reductase.

Melting Point
125-129°C
Solubility
Chloroform, Ethyl Acetate
References
Hoffman, W.F., et al.: J. Med. Chem., 29, 849 (1986), Mol, M.J., et al.: Lancet, 2, 936 (1986),
USBio References
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