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165139 N-(5-Adamant-1-yl-methoxy)pentyl Deoxynojirimycin| CAS: 216758-20-2�

Specifications
References
CAS Number
216758-20-2�
Grade
Highly Purified
Molecular Formula
C22H39NO5
Molecular Weight
397.55
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
RT/4°C
(2R,3R,4R,5S)-2-(Hydroxymethyl)-1-[5-(tricyclo[3.3.1.13,7]dec-1-ylmethoxy)pentyl]-3,4,5-piperidinetriol; �

A powerful inhibitor of the non-lysomal glucoceramidase at nanomolar concentrations. At these low concentrations, the lysosomal glucocerebrosidase and a-glucosidase, the glucoceramide synthetase, and the N-linked glycantrimming a-glucosidases of the endoplasmic reticulum are not affected.

Solubility
Ethanol, Methanol
Stability
Store Under Argon at -20°C
References
Jeckel, D., et al.: J. Cell Biol., 117, 259 (1992), Kato, A., et al.: J. Med. Chem., 48, 2036 (2005), Sakabe, K., et al.: J. Biol. Chem., 285, 34460 (2010),
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