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165912 Phenprocoumon CAS: 435-97-2

Specifications
References
CAS Number
435-97-2
Grade
Highly Purified
MDL Number
MFCD00865273
Molecular Formula
C₁₈H₁₆O₃
Molecular Weight
280.32
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
4°C
4-Hydroxy-3-(1-phenylpropyl)-2H-1-benzopyran-2-one; 3-(α-Ethylbenzyl)-4-hydroxy-coumarin; (±)-Phenprocoumon; 3-(1-Phenylpropyl)-4-hydroxycoumarin; 3-(α-Ethylbenzyl)-4-hydroxycoumarin; 3-(α-Phenylpropyl)-4-hydroxycoumarin; 4-Hydroxy-2-oxo-3-(1-phenylpropyl)-2H-chromene; BS 7565; DL-3-(α-Ethylbenzyl)-4-hydroxycoumarin; Falithrom; Fencumar; Liquamar; Marcoumar; Marcumar; Phenprocoumarol; Phenprocoumarole; Ro 1-4849

Phenprocoumon is known for being an oral anti-coagulant. Phenprocoumon is a coumarin derivative that inhibits vitamin K and acts as a long acting oral anticoagulant. It was recently found to act synergistically with flutamide to modulate the stability of the androgen receptor (AR) and resensitize AR-mutant prostate cancer cells to flutamide.

Synonyms
4-Hydroxy-3-(1-phenylpropyl)-2H-1-benzopyran-2-one; 3-(α-Ethylbenzyl)-4-hydroxy-coumarin; (±)-Phenprocoumon; 3-(1-Phenylpropyl)-4-hydroxycoumarin; 3-(α-Ethylbenzyl)-4-hydroxycoumarin; 3-(α-Phenylpropyl)-4-hydroxycoumarin; 4-Hydroxy-2-oxo-3-(1-phenylpropyl)-2H-chromene; BS 7565; DL-3-(α-Ethylbenzyl)-4-hydroxycoumarin; Falithrom; Fencumar; Liquamar; Marcoumar; Marcumar; Phenprocoumarol; Phenprocoumarole; Ro 1-4849
CAS No
435-97-2
Molecular Formula
C₁₈H₁₆O₃
Molecular Weight
280.32
Purity
≥98%
Appearance
White to off-white solid
Melting Point
173-176°C (lit)
Method for Determning Identity
Proton NMR Spectroscopic analysis
Storage and Stability
May be stored at RT for short-term only. Long-term storage is recommended at 4ºC for 6 months after time of receipt.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Toxicity and Hazards
 All products should be handled by qualified personnel only, trained in laboratory procedures.
References
Kohl, C. et al.: Drug. Metab. Disp., 28, 161 (2000)
USBio References
No references available
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