Prasugrel Hydroxy Thiolactone CAS 947502-66-1|

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166008 Prasugrel Hydroxy Thiolactone CAS: 947502-66-1|

Specifications

References

CAS Number

947502-66-1|

Grade

Highly Purified

Molecular Formula

C18H18FNO3S

Molecular Weight

347.4

EU Commodity Code

38220090

Shipping Temp

Storage Temp

RT/4°C

5-[2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-5,6,7,7a-tetrahydro-7a-hydroxythieno[3,2-c]pyridin-2(4H)-one;

Prasugrel Hydroxy Thiolactone, is the metabolite of Prasugrel� (P701150), which is a novel thienopyridine. It is also a potent inhibitor of platelet aggregation in vivo.

Melting Point

>45°C (dec.)

Solubility

DMSO

References

Von Beckerath, N., et al.: Circulation, 112, 2946� (2005), Jernberg, T., et al.: Eur. Heart J., 27, 1166� (2006), Farid, N., et al.: Drug Metab. Dispos., 35, 1096� (2007), Farid, N., et al.: Clin. Pharmacol. Ther., 81, 735� (2007), Jakubowski, J., et al.: J. Cardiovasc. Pharmacol., 49, 167� (2007), Wiviott, S., et al.: N. Engl. J. Med., 357, 2001� (2007),