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A0536-41 (1-Acetyl-2,2,5,5-tetramethyl-∆3-pyrroline-3-methyl) Methanethiosulfonate| CAS: 244641-23-4

Specifications
References
CAS Number
244641-23-4
Grade
Highly Purified
Molecular Formula
C₁₂H₂₁NO₃S₂
Molecular Weight
291.43
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
-20°C
S-[(1-Acetyl-2,5-dihydro-2,2,5,5-tetramethyl|-1H-pyrrol-3-yl)methyl] Ester

A highly reactive thiol-specific spin-label analogue. A specific conformational probe of thiol site structure by virtue of its minimal rotational freedom and distance from the covalent disulfide linkage to the macromolecule under study.

Synonyms
S-[(1-Acetyl-2,5-dihydro-2,2,5,5-tetramethyl -1H-pyrrol-3-yl)methyl] Ester
CAS No
244641-23-4
Molecular Formula
C₁₂H₂₁NO₃S₂
Molecular Weight
291.43
Purity
≥95%
Appearance
White to pale yellow solid
Melting Point
113-117°C (lit)
Solubility
Chloroform (Slightly), Methanol (Slightly)
Method for Determining Identity
Proton NMR Spectroscopic and Mass Spectrometric Analysis
TLC Conditions
SiO2; Dichloromethane: Methanol=9;1; Visualized with UV and AMCS; Single Spot, Rf=0.65
Storage and Stability
May be stored at RT for short-term only. Long-term storage is recommended at -20°C. Stable for 6 months after receipt.
References
1. Berengian, A., et al.: J. Biol. Chem., 274, 6305 (1999). 2. Gross, A., et al.: Biochemistry, 38, 10324 (1999). 3. Dobson, C., et al.: Nature, 426, 884 (2003). 4. Dong, J., et al: Science, 308, 1023 (2005)
USBio References
No references available
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