AIP, Recombinant, Human, aa1-330, His-Tag CAS

Grade

Purified

Accession Number

AAI04828

Molecular Weight

39.8

EU Commodity Code

30021019

Shipping Temp

Blue Ice

Storage Temp

-20°C

Aryl hydrocarbon receptor (AHR) interacting protein, also known as AIP, may play a positive role in AHR-mediated (aromatic hydrocarbon receptor) signaling, possibly by influencing its receptivity for ligand and/or its nuclear targeting. It is a Cellular negative regulator of the hepatitis B virus (HBV) X protein. Also, AIP is a ubiquitously expressed protein, binds to HSP 90 and AHR through a highly conserved carboxy-terminal tetraticopeptide repeat domain. Purified by using conventional chromatography techniques.

Recombinant protein corresponding to aa1-330 of human AIP, fused to His-tag at the N-terminal, expressed in E. coli (AAI04828).

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MADIIARLRE DGIQKRVIQE GRGELPDFQD GTKATFHYRT LHSDDEGTVL DDSRARGKPM ELIIGKKFKL PVWETIVCTM REGEIAQFLC DIKHVVLYPL VAKSLRNIAV GKDPLEGQRH CCGVAQMREH SSLGHADLDA LQQNPQPLIF HMEMLKVESP GTYQQDPWAM TDEEKAKAVP LIHQEGNRLY REGHVKEAAA KYYDAIACLK NLQMKEQPGS PEWIQLDKQI TPLLLNYCQC KLVVEEYYEV LDHCSSILNK YDDNVKAYFK RGKAHAAVWN AQEAQADFAK VLELDPALAP VVSRELRALE ARIRQKDEED KARFRGIFSH

Molecular Weight

~39.8kD (350aa), confirmed by MALDI-TOF

Storage and Stability

May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Source

Recombinant, E. coli

Purity

≥90% (SDS-PAGE)

Concentration

~1mg/ml

Form

Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, 1mM DTT, 10% glycerol

Important Note

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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A1059-87R AIP, Recombinant, Human, aa1-330, His-Tag (aryl hydrocarbon receptor interacting protein, ARA9, FKBP16, FKBP37, XAP2, HBV-X associated protein, aryl hydrocarbon receptor-interacting protein) CAS:

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