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A1350-01B Sheep Anti-Aldosterone

Specifications
References
Clone Type
Polyclonal
Host
Sheep
Isotype
IgG
Grade
Affinity Purified
Applications
E
Shipping Temp
Blue Ice
Storage Temp
-20°C

Aldosterone is a steroid hormone (mineralocorticoid family) produced by the outer-section (zona glomerulosa) of the adrenal cortex in the adrenal gland to regulate the bodies electrolyte and water balance. It is synthesized from cholesterol by aldosterone synthase, which is absent in other sections of the adrenal gland. It acts directly on the kidney to decrease the rate of sodium-ion excretion (with accompanying retention of water), and to increase the rate of potassium-ion excretion.

Applications
Suitable for use in ELISA. Other applications not tested.
Recommended Dilutions
ELISA: 1:300-1:5000 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Aldosterone conjugated to BSA
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein G affinity chromatography
Specificity
Recognizes Aldosterone. Exhibits a negligible reactivity with a range of associated hormones and derivitives.
References
1. Cronshaw, J. et al. (1989) Pre-natal development of the adrenal gland in the mallard duck (Anas platyrhynchos). Cell Tissue Res. 258(3): 593-601.
USBio References
No references available
Conjugates
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