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A3935-50B Rabbit Anti-Atg9A (Autophagy Related 9 Homolog A, APG9L1, FLJ22169, MGD3208)

Specifications
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
Q7Z3C6
Isotype
IgG
Grade
Affinity Purified
Applications
WB
Crossreactivity
Hu
Shipping Temp
Blue Ice
Storage Temp
-20°C
Autophagy-related Protein 9A, APG9-like 1, Cytoplasm to Vacuole Targeting Protein 7, Autophagy-related Protein 9, APG9A

Survival of environmental stress conditions requires the maintenance of cellular homeostasis. To preserve this balance, cells utilize a degradative mechanism known as autophagy. During this process, in response to starvation or other stresses, bulk cytoplasm is non-specifically sequestered within double-membrane vesicles and delivered to the lysosome/vacuole for subsequent degradation and recycling. Atg9 is the only integral membrane protein required for autophagosome formation and considered a membrane carrier in autophagy-related pathways.

Applications
Suitable for use in Western Blot. Other applications not tested.
Recommended Dilution
Optimal dilutions to be determined by the researcher.
Cellular Localization: Membrane; multi-pass membrane protein.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Synthetic peptide made to a region within the C-terminus of the human protein (between residues 750-839).
Form
Supplied as a liquid in PBS, 0.02% sodium azide
Purity
Purified by immunoaffinity chromatography.
Specificity
Recognizes human ATG9A protein (Mr ~95kD). Species Sequence Homology: 100% (monkey, mouse, rat, and cow); 94% (chicken)
Conjugates
Pricing
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