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C8860-01 Cyclopiazonic Acid CAS: 18172-33-3

Specifications
CAS Number
18172-33-3
Grade
Highly Purified
Molecular Formula
C20H20N2O3
Molecular Weight
336.4
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
-20°C

Cyclopiazonic acid is a tremorigenic indole produced by several species of the genera Aspergillus and Penicillium. Cyclopiazonic acid is a highly specific inhibitor of calcium ATPase of sarcoplasmic reticulum, altering calcium homeostasis and ATP-dependent calcium transport and resulting in the induction of release of intracellular stored Ca2+ without increasing IP3.

Source
Cylcopiazonic acid from Penicillium griseofulvum.
Molecular Weight
~336.4
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.
Storage and Stability
Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with DMSO. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Purity
~98% (HPLC)
Concentration
Not determined
Form
Supplied as an off-white powder.
Pricing
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