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D3441-58 2,4-Diacetylphloroglucinol (DAPG) CAS: 2161-86-6

Specifications
References
CAS Number
2161-86-6
Grade
Highly Purified
Molecular Formula
C10H10O5
Molecular Weight
210.18
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
-20°C
DAPG; 1,1'-(2,4,6-Trihydroxy-1,3-phenylene)bis-ethanone; 1,3-Diacetyl-2,4,6-trihydroxybenzene; 5-Acetyl-2,4,6-trihydroxyacetophenone

A secondary metabolite of P. Fluorescens strain CHAO which is a pathogen suppressor as well as showing inhibitory effects on bacteria, fungi, and plants.

Synonyms
DAPG; 1,1'-(2,4,6-Trihydroxy-1,3-phenylene)bis-ethanone; 1,3-Diacetyl-2,4,6-trihydroxybenzene; 5-Acetyl-2,4,6-trihydroxyacetophenone
CAS No
2161-86-6
Molecular Formula
C10H10O5
Molecular Weight
210.18
Purity
≥98%
Appearance
As reported
Solubility
DMF: 30mg/ml; DMF:PBS (pH 7.2)(1:1): 0.5mg/ml; DMSO: 15mg/ml; Ethanol: 25mg/ml Poor water solubility. Solution should be purged with an inert gas. Prepare working solution daily.
Storage and Stability
May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Toxicity and Hazards
 All products should be handled by qualified personnel only, trained in laboratory procedures.
References
1. Keel, C., Ursula, S., Maurhofer, M., et al. Suppression of root diseases by Pseudomonas fluorescens CHA0: Importance of the bacterial seconday metabolite 2,4-diacetylphloroglucinol. Mol. Plant Microbe Interact. 5(1), 4-13 (1995). 2. Veena, V.K., Popavath, R.N., Kennedy, K., et al. In vitro antiproliferative, pro-apoptotic, antimetastatic and anti-inflammatory potential of 2,4-diacetylphloroglucinol (DAPG) by Pseudomonas aeruginosa strain FP10. Apoptosis 20(10), 1281-1295 (2015).
USBio References
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