USBio Logo

D9025-01 Doramectin CAS: 117704-25-3

Specifications
CAS Number
117704-25-3
Grade
Highly Purified
Molecular Formula
C50H74O14
Molecular Weight
899.1
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
-20°C

Doramectin is a biosynthetic avermectin derived from a mutant of the original Streptomyces avermitilis strain supplemented with a cyclohexylcaboxylic acid starting unit. Doramectin was developed as an anthelmintic for internal parasite control. The presence of the cyclohexyl group replacing the sec-butyl moiety affords greater hydrophobicity and longer biological half-life compared to avermectin. Like the other milbemycin/avermectins, it selectively binds to parasite glutamate-gated chloride ion channels and disrupts neurotransmission leading to paralysis and death of the parasite.

Source
Doramectin from Streptomyces sp., biosynthetic.
Molecular Weight
~899.1
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.
Storage and Stability
Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with DMSO. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Purity
~95% (HPLC)
Concentration
Not determined
Form
Supplied as a white solid.
Pricing
Order
Proceed to Checkout
Cart Summary
ProductSizeListYour PriceQtyExt Price
Subtotal:Subtotal:
Subtotal:Subtotal:
Total Coupon Savings:Total Coupon Savings:()
Your cart is currently empty.
- Coupon Code
Recently Viewed
  • Contact Us

    Visit our technical library or contact our support staff to answer your questions.

    Telephone:
    1-800-520-3011

    Library | Contact

    Distributors

    For customers outside of the United States, please use one of our many distributors.

    View Distributors

    Payment Methods

    We accept the following payment methods as well as pay-by-invoice.

    MasterCard Visa PayPal
    © 2023-2024 United States Biological - All Rights Reserved