DTX1

Clone Type

Polyclonal

Host

Goat

Source

Human

Isotype

IgG

Grade

Affinity Purified

Applications

Crossreactivity

Accession #

NP_004407.2

Shipping Temp

Blue Ice

Storage Temp

-20°C

deltex homolog 1, hDx-1, deltex homolog 1 (Drosophila), DTX1

Studies in Drosophila have identified this gene as encoding a positive regulator of the Notch-signaling pathway. The human gene encodes a protein of unknown function; however, it may play a role in basic helix-loop-helix transcription factor activity.

Applications

Suitable for use in ELISA. Other applications have not been tested.

Recommended Dilutions

Peptide ELISA Titer: 1:8000 Optimal dilutions to be determined by the researcher.

Storage and Stability

May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunogen

Synthetic peptide corresponding to CHHIENVLKEDAR, from the internal region (near N Terminus) of human DTX-1 (NP_004407.2).

Form

Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.

Purity

Purified by peptide affinity chromatography.

Specificity

Recognizes DTX1. Species sequence homology: human, mouse, rat, canine, bovine.

References

1. Gupta-Rossi N, Storck S, Griebel PJ, Reynaud CA, Weill JC, Dahan A, Specific over-expression of deltex and a new Kelch-like protein in human germinal center B cells. Molecular immunology 2003 Mar 39 (13): 791-9.