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G1043-05S Goat Anti-Galanin Receptor 1 (Galanin Receptor Type 1, GAL1-R, GALNR, GALNR1, GALR1, GALR-1)

Specifications
References
Clone Type
Polyclonal
Host
Goat
Source
Rat
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Bo Ca Hu Mo Rt
Accession #
NP_001471.2
Gene ID
2587, 14427, 50577
Shipping Temp
Blue Ice
Storage Temp
-20°C

Receptor for the hormone galanin. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.

Applications
Suitable for use in ELISA and Western Blot. Other applications not tested.
Recommended Dilution
ELISA: 1:128,000 Western Blot: 0.1-0.3ug/ml, observed in lysates of rat spinal cord on ~24-25, 37kD bands Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Synthetic peptide corresponding to C-RSKPGKPRSTTN, from rat GALR1 at the internal region of the protein (NP_001471.2).
Form
Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Purity
Purified by immunoaffinity chromatography.
Specificity
Recognizes rat GALR1. Species sequence homology: Bovine, canine, human and mouse.
References
1. Henson BS, Neubig RR, Jang I, Ogawa T, Zhang Z, Carey TE, D\1Silva NJ. Galanin receptor 1 has anti-proliferative effects in oral squamous cell carcinoma. J Biol Chem. 2005 Jun 17;280(24):22564-71. Epub 2005 Mar 14.
USBio References
No references available
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