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G2035-16 TNFSF18, Recombinant, Human, aa72-199 (Tumor Necrosis Factor Ligand Superfamily Member 18, Activation-inducible TNF-related Ligand, AITRL, Glucocorticoid-induced TNF-related Ligand, hGITRL, AITRL, GITRL, TL6, UNQ149/PRO175) CAS:

Specifications
References
Grade
Purified
Accession Number
NP_005083
Molecular Weight
14.6
EU Commodity Code
30021019
Shipping Temp
Blue Ice
Storage Temp
-20°C

TNFSF18, belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It is Important for interactions between activated T-lymphocytes and endothelial cells and may modulate T-lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells.

Source
Recombinant corresponding to aa72-199 from human TNFSF18 expressed in E.coli.
Amino Acid Sequence
MQLETAKEPC MAKFGPLPSK WQMASSEPPC VNKVSDWKLE ILQNGLYLIY GQVAPNANYN DVAPFEVRLY KNKDMIQTLT NKSKIQNVGG TYELHVGDTI DLIFNSEHQV LKNNTYWGII LLANPQFIS
Molecular Weight
~14.6kD (MALDI-TOF)
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Source
Recombinant, E. coli
Purity
≥90% (SDS-PAGE)
Concentration
~0.5mg/ml
Form
Supplied as a liquid in 10mM sodium citrate, pH 3.5, 10% glycerol, 1mM DTT.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
References
1. Kwon B, et al. (1999) J Biol Chem 274(10):6056.
USBio References
No references available
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