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G8989-39C Rabbit Anti-GDF3, NT (Growth/Differentiation Factor 3, GDF-3, UNQ222/PRO248)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
Q9NR23
Isotype
IgG
Grade
Purified
Applications
E IHC WB
Crossreactivity
Hu Mo
Accession #
NP_065685
Shipping Temp
Blue Ice
Storage Temp
-20°C

GDF3 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. The function of this protein is unknown, but expression studies suggest it may be involved in regulation of the adult lymphatic and erythroid systems and embryonic development.

Applications
Suitable for use in ELISA, Western Blot, and Immunohistochemistry. Other applications not tested.
Recommended Dilutions
ELISA: 1:1000 Western Blot: 1:100-1:500 Immunohistochemistry (Paraffin): 1:50-1:100 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Synthetic peptide corresponding to a portion of amino acids within aa29-59 from the N-terminal region of human GDF3, conjugated to KLH.
Form
Supplied as a liquid in PBS, 0.09% sodium azide.
Purity
Purified by ammonium sulfate precipitation
Specificity
Recognizes human GDF3. Species Crossreactivity: mouse
References
1. Clark, H.F., et al., Genome Res. 13(10):2265-2270 (2003). 2. Ducy, P., et al., Kidney Int. 57(6):2207-2214 (2000). 3. Caricasole, A.A., et al., Oncogene 16(1):95-103 (1998).
USBio References
No references available
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