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H8995-02 Hydrochlorothiazide Impurity C CAS: 402824-96-8

Specifications
References
CAS Number
402824-96-8
Grade
Highly Purified
Molecular Formula
C15H16Cl2N6O8S4
Molecular Weight
607.49
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
-20°C
N-[[7-(Aminosulfonyl)-6-chloro-2,3-dihydro-1,1-dioxo-4H-1,2,4-benzothiadiazin-4-yl]methyl]-6-chloro-3,4-dihydro-1,1-dioxo-2H-1,2,4-benzothiadiazine-7-sulfonamide

An impurity in bulk Hydrochlorothiazide. Dimer Impurity C.

Synonyms
N-[[7-(Aminosulfonyl)-6-chloro-2,3-dihydro-1,1-dioxo-4H-1,2,4-benzothiadiazin-4-yl]methyl]-6-chloro-3,4-dihydro-1,1-dioxo-2H-1,2,4-benzothiadiazine-7-sulfonamide
CAS No
402824-96-8
Molecular Formula
C15H16Cl2N6O8S4
Molecular Weight
607.49
Appearance
White to off-white solid
Purity
≥90%
Melting Point
211-218˚C
Method for Determining Identity
Proton NMR (DMSO-d6) Spectroscopic and Mass Spectrometric Analysis
TLC Conditions
As Reported
Solubility
Aqueous Acid (Slightly), DMSO (Slightly), Methanol (Slightly)
Storage and Stability
May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Source
Synthetic
Purity
~90%
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
References
1. Daniels, S.L., et al. J. Pharm. Sci., 70, 211 (1981). 2. Fang, X., et al. Pharm. Res., 14, 691 (1997).
USBio References
No references available
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